The science of hormonally changing skin.

The science behind MenoCore

The science of hormonally changing skin.

Nature and science, considered together. Wild yam meets hydration, skin-conditioning ingredients and barrier lipids.

The MenoCore complex

Ten featured ingredients. One considered formula.

Nature

  • Wild yam extract
  • Centella asiatica
  • Vitex agnus-castus
  • Aloe vera
  • Borage seed oil
Ring of MenoCore ingredient textures: wild yam root, centella leaves, vitex blossom, aloe and borage blending into cream, clear gel, water droplets and golden plant oils

Science

  • Ceramide complex
  • Niacinamide
  • Hyaluronic acid
  • Squalane
  • Vitamin E

Balance

Ten featured ingredients from the complete MenoCore formula.

One considered formula

Each ingredient has a role.

Explore the botanical extracts, hydration system and lipids behind the cream.

01Botanical ingredients

Wild yam extract, Centella asiatica, Vitex agnus-castus, aloe vera and borage seed oil. A blend of extracts and plant oil within the complete skin-conditioning formula.

02Hydration and skin conditioning

Niacinamide and sodium hyaluronate. Selected alongside glycerin and propanediol for hydrated skin feel and their documented cosmetic roles.

03Lipids and emollience

Ceramides AP, EOP and NP, squalane and vitamin E. The three ceramides sit alongside cholesterol and phytosphingosine; squalane contributes softness and spread.

“Nature” and “Science” describe the visual story, rather than a strict division by ingredient origin. Squalane and vitamin E can come from different sources. The supplied material determines their origin.

Explore the 18 featured functional ingredients

Wild yam root extract; niacinamide; glycerin; propanediol; sodium hyaluronate; squalane; cocoa butter; avocado oil; borage seed oil; aloe leaf juice; ceramides AP, EOP and NP; cholesterol; phytosphingosine; Centella asiatica extract; bisabolol; and tocopherol.

Interactive skin map

Where cosmetic care meets changing skin.

Explore the skin layers and the formulation roles of lipids, humectants and skin-conditioning ingredients.

Skin structure and cosmetic ingredient roles A schematic of the outer barrier, epidermis and dermis, with a separate illustration of water-binding ingredients and emollients. It does not show measured delivery of MenoCore into the skin. Outer barrierStratum corneum EpidermisDermis Moisture + lipidsIngredient roles
Conceptual illustration, not a finished-product penetration study. Moisture and lipids are ingredient roles, not an additional anatomical skin layer.
01 / Stratum corneum: the barrier

Ceramides AP, EOP and NP, cholesterol and phytosphingosine are the formula's barrier-minded lipid components.

02 / Epidermis: surface care

Wild yam and niacinamide belong to the ingredient story. Laboratory diosgenin research is not proof of renewal, hormone activity or delivery in the finished cream.

03 / Dermis: the evidence boundary

Centella asiatica is a skin-conditioning ingredient. Its presence does not establish delivery to the dermis or increased collagen in people using MenoCore.

04 / Lipids and hydration

Sodium hyaluronate, glycerin and propanediol are humectants. Borage, cocoa and avocado ingredients and squalane contribute emollience and skin feel, not demonstrated deep-skin delivery.

Illustrative cosmetic-care map, not a penetration study. Ingredient positions explain formulation roles and do not demonstrate delivery to, or biological activity within, a particular skin depth.

A clearer comparison

MenoCore vs others.

Beyond wild yam, here is what MenoCore adds to the daily skin-care formula.

Cream, wild yam root and Centella leaves in a formulation setting
What to compareMenoCoreOthers*
Barrier lipids

Three named ceramides—AP, EOP and NP—plus cholesterol and phytosphingosine.

These ingredients are not listed in the comparison cream's published formula.

Hydration and skin feel

Niacinamide, sodium hyaluronate and squalane alongside glycerin, propanediol and nourishing oils.

Has moisturising ingredients including aloe and avocado oil, but does not list niacinamide, sodium hyaluronate or squalane.

Two textures, one routine

A lighter MenoCore 10 and richer MenoCore 20, each in a 100 ml airless pump, designed for face and body.

The comparison listing offers one 100 g wild yam cream and does not describe an airless pack or paired day/evening textures.

*“Others” uses one directly comparable published product listing as an example, checked 27 September 2026. Source. It states 200 mg of liquid wild yam extract per gram; MenoCore states 10% or 20% of its complete supplied extract material. These figures do not establish which extract or cream is stronger. This is a published-formula comparison, not a test of performance.

Published research

The research

Published studies inform the formulation. They are not clinical results for the finished MenoCore creams.

Menopause, skin structure and barrier lipids
  1. Calleja-Agius J, Muscat-Baron Y, Brincat MP. Skin ageing. Menopause International. 2007;13(2):60-64.
  2. Kendall AC, et al. Menopause induces changes to the stratum corneum ceramide profile, which are prevented by hormone replacement therapy. Scientific Reports. 2022;12:21715.
  3. Thornton MJ. Estrogens and aging skin. Dermato-Endocrinology. 2013;5(2):264–270.
Wild yam and diosgenin
  1. Komesaroff PA, Black CV, Cable V, Sudhir K. Effects of wild yam extract on menopausal symptoms, lipids and sex hormones. Climacteric. 2001;4(2):144–150.
  2. Tada Y, et al. Novel effects of diosgenin on skin aging. Steroids. 2009;74(6):504-511. Laboratory and animal research, not a finished MenoCore cream trial.
  3. Andersen FA, ed. Final report of the amended safety assessment of Dioscorea villosa root extract. Int J Toxicol. 2004;23(Suppl 2):49–54.
  4. Raj PS, et al. Dioscorea villosa (wild yam) root extract. Int J Toxicol. 2023;42(3 Suppl):29S–31S.
Barrier-supporting ingredients
  1. Tanno O, et al. Nicotinamide increases biosynthesis of ceramides and other stratum corneum lipids. Br J Dermatol. 2000;143(3):524–531.
  2. Soma Y, et al. Moisturizing effects of topical nicotinamide on atopic dry skin. Int J Dermatol. 2005;44(3):197–202.
  3. Bissett DL, et al. Niacinamide: a B vitamin that improves aging facial skin appearance. Dermatol Surg. 2005;31:860–865.
  4. De Paepe K, et al. Repair of damaged human skin barrier using emulsions containing barrier lipids. JEADV. 2002;16(6):587–594.
  5. Pavicic T, et al. Efficacy of hyaluronic acid formulations of different molecular weights. J Drugs Dermatol. 2011;10(9):990–1000.
  6. Bylka W, et al. Centella asiatica in cosmetology. Postepy Dermatol Alergol. 2013;30(1):46–49.
  7. Maurya AK, et al. Alpha-bisabolol reduces pro-inflammatory cytokine production. Curr Pharm Biotechnol. 2014;15(2):173–181.

Evidence reviewed September 2026.

Our standard
The truth is not a limitation of a science-led brand. It is the standard.
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